A Critical Overview of the Validity of the Current Concept of Bipolar Disorder
Diego J. Martino, Alejandro G. Szmulewicz, Boris Birmaher · 2025
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Description
Martino, Szmulewicz, and Birmaher ask in twenty twenty-five whether today's concept of bipolar disorder rests on valid ground. They reviewed a century of texts and studies on the criteria for manic and depressive episodes, judging both whether the illness is a real entity and whether the rules describe it well.
Mania holds up as a genuine construct, though its diagnostic rules need more testing. Evidence for splitting milder hypomania from mania as separate episodes is thin and contested. The modern idea of bipolar depression lumps together unlike episode types, with weak proof all belong to the one illness. The authors call the current definition's validity limited. Sharper definitions, they argue, would speed biology research and tailored treatment.
Catalog record
| CREATOR | Diego J. Martino, Alejandro G. Szmulewicz, Boris Birmaher |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |