Physical Function, Muscle Strength, and Fatigue in Patients with Multiple Sclerosis: An Exploratory Cross-Sectional Study
Olimar Leite de Assis Cunha, Luciane Coral Siciliani, Marcelo Barbosa Anzanel, Whesley Tanor Silva, Tatiana Rehder Gonçalves, Mauro Felippe Felix Mediano, Marina Papais Alvarenga, Regina Maria Papais Alvarenga, Hélcio Alvarenga Filho, Jorge Morais · 2025
Read Physical Function, Muscle Strength, and Fatigue in Patients with Multiple Sclerosis: An Exploratory Cross-Sectional Study by Olimar Leite de Assis Cunha, Luciane Coral Siciliani, Marcelo Barbosa Anzanel, Whesley Tanor Silva, Tatiana Rehder Gonçalves, Mauro Felippe Felix Mediano, Marina Papais Alvarenga, Regina Maria Papais Alvarenga, Hélcio Alvarenga Filho, Jorge Morais (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12734181.txt.
Description
Multiple sclerosis often leaves people weaker, slower, and worn out, and Cunha and co-authors set out to measure how those three problems hang together. Their 2025 study compared patients with the relapsing-remitting form of the disease against a control group. Tests covered walking, balance, disability scores, knee strength, and fatigue measured with a load cell.
Patients walked worse, pushed weaker, and tired faster than controls. Knee extension fatigue tied to all three function scores: the gait index, the two-minute walk, and the disability scale. Knee strength tied to disability scores as well. The authors read knee muscles as a key weak point in this disease and a natural target for therapy that aims to keep patients moving. They note the study is exploratory, so the links need testing in larger groups.
Catalog record
| CREATOR | Olimar Leite de Assis Cunha, Luciane Coral Siciliani, Marcelo Barbosa Anzanel, Whesley Tanor Silva, Tatiana Rehder Gonçalves, Mauro Felippe Felix Mediano, Marina Papais Alvarenga, Regina Maria Papais Alvarenga, Hélcio Alvarenga Filho, Jorge Morais |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |