Non-Fistulizing Perianal Disease in Crohn’s Disease: Clinical Significance, Pathogenesis, and Management Strategies
Inês Abreu Marques, Tiago Cúrdia Gonçalves, Cláudia Macedo, Pedro Campelo, José Cotter, Andrew Day, Hidekazu Suzuki · 2025
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Description
Ines Abreu Marques and co-authors present a 2025 review of a less known side of Crohn's disease: perianal damage that does not form fistulas. Cracks, deep ulcers, narrowings, and skin tags near the anus affect many patients and drag down daily life. The review pulls work up to late 2025 that sets these apart from fistula cases.
Close to half of patients develop such signs during their illness. Many heal with standard Crohn's care or simple measures. Deep ulcers and narrowings warn of a rougher course. Surgery is kept for stubborn cases, since risk is high. A link to anal cancer stays unproven. The authors call for set labels, closer watch, and trials of modern drugs.
Catalog record
| CREATOR | Inês Abreu Marques, Tiago Cúrdia Gonçalves, Cláudia Macedo, Pedro Campelo, José Cotter, Andrew Day, Hidekazu Suzuki |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |