Expanded Hemodialysis with Theranova 500 Improves Dialysis Adequacy and Blunts Inflammation: A 24-Week Quasi-Randomized Trial
Nomy Levin Iaina, Elena Rotshild, Sharon Mini Goldberg, Pazit Beckerman, Maurizio Bossola · 2025
Read Expanded Hemodialysis with Theranova 500 Improves Dialysis Adequacy and Blunts Inflammation: A 24-Week Quasi-Randomized Trial by Nomy Levin Iaina, Elena Rotshild, Sharon Mini Goldberg, Pazit Beckerman, Maurizio Bossola (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12733824.txt.
Description
Nomy Levin Iaina and co-authors report a trial in two thousand twenty-five of an expanded dialysis filter for kidney failure patients. Standard dialysis clears small toxins but leaves middle-sized molecules that drive inflammation and symptoms. A medium-cutoff dialyzer, Theranova 500, is built to remove those larger toxins.
Forty patients at two Israeli centers were assigned in sequence to the new filter or a standard high-flux one for twenty-four weeks. Dialysis adequacy rose clearly in the new-filter group, from about one point two four to one point four zero on the standard index, while the comparison group barely moved. Inflammation, tracked by C-reactive protein, stayed flat with the new filter but nearly tripled without it. Other measures, including albumin and weight, stayed stable in both groups.
Catalog record
| CREATOR | Nomy Levin Iaina, Elena Rotshild, Sharon Mini Goldberg, Pazit Beckerman, Maurizio Bossola |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |