Biomimetic Glycosaminoglycan-Enriched Electrospun Polymeric Scaffolds for Enhanced Early Tissue Regeneration
Morgane Meyer, Rana Smaida, Henri Favreau, Cristina Yus, Hervé Gegout, Manuel Arruebo, Nadia Bahlouli, Guy Ladam, Guillaume Conzatti, Stephan Lemmens, Guoqiang Hua, Florence Fioretti, Nadia Benkirane-Jessel · 2025
Read Biomimetic Glycosaminoglycan-Enriched Electrospun Polymeric Scaffolds for Enhanced Early Tissue Regeneration by Morgane Meyer, Rana Smaida, Henri Favreau, Cristina Yus, Hervé Gegout, Manuel Arruebo, Nadia Bahlouli, Guy Ladam, Guillaume Conzatti, Stephan Lemmens, Guoqiang Hua, Florence Fioretti, Nadia Benkirane-Jessel (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12733769.txt.
Description
Meyer and a large team built a tissue scaffold for early joint repair in twenty twenty-five. The scaffold is an implant meant to help damaged tissue regrow, aimed at osteoarthritis, a widespread joint disease that worsens from small early lesions. Prevention options for that early stage are few.
The scaffold is a fine fiber membrane spun from a medical polymer. It is enriched with glycosaminoglycans, sugar-rich molecules including hyaluronic acid and chondroitin sulfate found in cartilage. These mimic the natural matrix around cartilage cells. The team measured the scaffold's structure, strength, water behavior, and stability. Lab tests checked that cells tolerate it and interact well with it. The authors present the design as a preventive strategy to preserve joint function, pending clinical translation.
Catalog record
| CREATOR | Morgane Meyer, Rana Smaida, Henri Favreau, Cristina Yus, Hervé Gegout, Manuel Arruebo, Nadia Bahlouli, Guy Ladam, Guillaume Conzatti, Stephan Lemmens, Guoqiang Hua, Florence Fioretti, Nadia Benkirane-Jessel |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 65 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |