Neural correlates of decision making and executive function in suicidal thoughts and behaviors
Fangfang Tian, Lu Zhou, Xiuli Wang, Neil Roberts, Hua Pang · 2025
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Description
People at risk of suicide often struggle with choices and with mental control, and brain scans may show why. Fangfang Tian, Lu Zhou, Xiuli Wang, Neil Roberts, and Hua Pang gathered the published imaging studies of decision making and executive function in patients with suicidal thoughts and behaviors. They pooled the results with a coordinate based meta-analysis method that maps where brain activity differed from patient comparison groups.
One region stood out in both kinds of task: the left anterior cingulate cortex ran unusually hot. Decision tasks also showed changes in the insula and hippocampus, while control tasks added a motor region. The authors read this as evidence that faulty decision making, more than general control problems, sits near the core of suicide risk, and they point to therapies targeting choices and impulsivity.
Catalog record
| CREATOR | Fangfang Tian, Lu Zhou, Xiuli Wang, Neil Roberts, Hua Pang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |