Cysteine Attenuates Intestinal Inflammation by Regulating the Gut Microbiota and TLR4-JNK/MAPK-NF-κB Pathway in Piglets
Rui Liu, Pengxiang Qin, Zihao Liu, Wenjing Liu, Shuzhen Jiang, Xuejun Yuan, Weiren Yang, Caiyun Huang, Ning Jiao · 2025
Read Cysteine Attenuates Intestinal Inflammation by Regulating the Gut Microbiota and TLR4-JNK/MAPK-NF-κB Pathway in Piglets by Rui Liu, Pengxiang Qin, Zihao Liu, Wenjing Liu, Shuzhen Jiang, Xuejun Yuan, Weiren Yang, Caiyun Huang, Ning Jiao (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12732415.txt.
Description
Rui Liu and co-authors show that the amino acid cysteine calms gut inflammation in piglets harmed by a plastic chemical, in work from twenty twenty-five. Cysteine guards against oxidative damage and supports the gut barrier. How it fights intestinal inflammation was unclear.
Twenty-four piglets ate diets with or without the chemical BPA and with or without cysteine for four weeks. Cysteine restored the small intestine barrier, raising cell growth and mucus cell counts while cutting cell death. Inflammatory signals in blood and gut fell. Gut microbe balance and short chain fat levels recovered too. A key alarm pathway quieted to normal. The authors call cysteine a nutritional lever against gut injury.
Catalog record
| CREATOR | Rui Liu, Pengxiang Qin, Zihao Liu, Wenjing Liu, Shuzhen Jiang, Xuejun Yuan, Weiren Yang, Caiyun Huang, Ning Jiao |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |