Sleep in Lennox–Gastaut Syndrome: A Scoping Review

Debopam Samanta · 2025

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Description

Debopam Samanta maps everything known about sleep in Lennox-Gastaut syndrome, a severe childhood epilepsy, in this scoping review from twenty twenty-five. The syndrome brings many seizure types, abnormal brain waves, and cognitive impairment. Bad sleep is nearly universal in it, yet no one had charted the whole picture.

Eleven studies survived screening from over twelve hundred candidates, spanning four decades and four continents, most of them tiny. The pattern is stark: dream sleep is reduced or missing, deep sleep is fragmented, and the micro-structure of sleep is unstable, with seizure discharges clustering in its restless phases. Breathing disorders in sleep are common, especially in adults, and body-clock hormones run off-schedule. Wearable home monitors proved workable in these children. One gap stands out: no trial has tested whether fixing sleep improves seizures or thinking. The author calls for large studies that try.

Catalog record

CREATORDebopam Samanta
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12732266

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