Corn Bran IDF and Polyphenol-Reduced IDF Alleviate Low-Dose 3-MCPD-Induced Toxicity by Modulating Gut Microbiota and Intestinal Barrier

Zhiqiang Song, Huanxiao Jiang, Huiying Dai, Liying Bo, Chunli Song, Xiaolan Liu, Jian Ren, Marcio Schmiele · 2025

Read Corn Bran IDF and Polyphenol-Reduced IDF Alleviate Low-Dose 3-MCPD-Induced Toxicity by Modulating Gut Microbiota and Intestinal Barrier by Zhiqiang Song, Huanxiao Jiang, Huiying Dai, Liying Bo, Chunli Song, Xiaolan Liu, Jian Ren, Marcio Schmiele (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12732245.txt.

Description

Zhiqiang Song and co-authors test whether corn bran fiber can blunt the harm of a common food contaminant, in a 2025 study. The contaminant, 3-MCPD, forms during oil refining and shows up in many processed foods. Corn bran's insoluble fiber carries polyphenols, plant chemicals with protective effects, but it was unclear whether the fiber helps without them.

Mice on low doses of the contaminant received plain fiber or a treated fiber stripped of most polyphenols. Both fibers eased movement problems, calmed colon inflammation, and strengthened the gut barrier, even though the stripped fiber had lost much of its antioxidant power. Gut microbe profiles shifted between groups without losing diversity. The results suggest the fiber's physical presence in the gut, not just its chemical passengers, does much of the protecting.

Catalog record

CREATORZhiqiang Song, Huanxiao Jiang, Huiying Dai, Liying Bo, Chunli Song, Xiaolan Liu, Jian Ren, Marcio Schmiele
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12732245

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