Evaluating the CRP Interactome: Insights into Possible Novel Roles in Cellular Signaling and Tumorigenicity
Alison Gerhardt, Dlen Nanakaliy, Harnish D. Shah, Syed Sarfaraz, Charlotte Madigan, Makenna Downing, Robert P. Elliott, Rafid Dipto, Bella Vrapciu, Joseph W. Noetzel, Jessica Armas, Ayesha Ahmed, Marc Potempa, Margaret E. Olson, Lawrence A. Potempa, Peter C. Hart · 2025
Read Evaluating the CRP Interactome: Insights into Possible Novel Roles in Cellular Signaling and Tumorigenicity by Alison Gerhardt, Dlen Nanakaliy, Harnish D. Shah, Syed Sarfaraz, Charlotte Madigan, Makenna Downing, Robert P. Elliott, Rafid Dipto, Bella Vrapciu, Joseph W. Noetzel, Jessica Armas, Ayesha Ahmed, Marc Potempa, Margaret E. Olson, Lawrence A. Potempa, Peter C. Hart (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12732217.txt.
Description
Alison Gerhardt and co-authors map in 2025 the web of proteins that interact with a famous inflammation marker, hunting for new roles in signaling and cancer. The marker rises in the blood during inflammation and is used to gauge it. Its several forms help start, boost, and settle inflammation.
Within tissues, the protein talks across many cell kinds, from surface and vessel cells to fat and immune cells. That chatter shapes settings where cancer can grow under inflammatory cover. The team's map of its partners suggests jobs beyond a passive marker, in active signaling. If the protein helps drive tumor friendly signaling, then its partners become drug targets. The study also frames tests to separate cause from mere association.
Catalog record
| CREATOR | Alison Gerhardt, Dlen Nanakaliy, Harnish D. Shah, Syed Sarfaraz, Charlotte Madigan, Makenna Downing, Robert P. Elliott, Rafid Dipto, Bella Vrapciu, Joseph W. Noetzel, Jessica Armas, Ayesha Ahmed, Marc Potempa, Margaret E. Olson, Lawrence A. Potempa, Peter C. Hart |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |