Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular Carcinoma

Faris Alrumaihi, Reem A. Alromaihi, Vikalp Kumar, Shehwaz Anwar · 2025

Read Cancer Vaccines: Molecular Mechanisms, Clinical Progress, and Combination Immunotherapies with a Focus on Hepatocellular Carcinoma by Faris Alrumaihi, Reem A. Alromaihi, Vikalp Kumar, Shehwaz Anwar (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12732165.txt.

Description

Faris Alrumaihi and three co-authors wrote a 2025 review of cancer vaccines, with a focus on liver cancer. Standard treatments often fail because tumors suppress the immune system around them. Vaccines aim to train killer immune cells to attack the tumor and to leave lasting memory. The review covers the molecular mechanisms behind the approach and the clinical progress of vaccine types built from nucleic acids, peptides, and dendritic cells.

Pairing vaccines with checkpoint inhibitors or tissue-destroying therapies strengthens and lengthens the response, the authors report. Liver cancer is a natural target: survival is poor and options are few. Better antigen discovery and delivery systems are widening what vaccines can do. The authors argue that vaccines may shift liver cancer care from short-term control toward durable management.

Catalog record

CREATORFaris Alrumaihi, Reem A. Alromaihi, Vikalp Kumar, Shehwaz Anwar
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE108 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12732165

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