Maintenance and Decline of Neuronal Lysosomal Function in Aging
Ruiling Zhong, Claire E. Richardson · 2025
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Description
Ruiling Zhong and Claire Richardson review the cell's waste hubs in aging nerve cells in a 2025 paper. Those hubs, called lysosomes, shred worn parts and spent clumps, recycle the bits, and send growth signals. Nerve cells live long, stretch far, and burn much fuel, so their hubs bear a heavy, lasting load.
How hub power is kept up with age, and where it fails in sound nerve cells, was little mapped next to the vast work on brain ills. The review sums what is known of hub flow in youth and age. It also flags the hard parts of gauging hub work in live cells.
Catalog record
| CREATOR | Ruiling Zhong, Claire E. Richardson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |