The Potential Clinical Relevance of Necrosis–Necroptosis Pathways for Hypoxic–Ischaemic Encephalopathy

Benjamin A Lear, Alice J McDouall, Olivia J Lear, Simerdeep K Dhillon, Christopher A Lear, Frances J Northington, Laura Bennet, Alistair J Gunn, Thomas Müller · 2025

Read The Potential Clinical Relevance of Necrosis–Necroptosis Pathways for Hypoxic–Ischaemic Encephalopathy by Benjamin A Lear, Alice J McDouall, Olivia J Lear, Simerdeep K Dhillon, Christopher A Lear, Frances J Northington, Laura Bennet, Alistair J Gunn, Thomas Müller (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12731611.txt.

Description

Lear and eight co-authors weigh cell-death paths as cure marks for birth brain harm in this twenty twenty-five review. Such harm hits babes whose brains lost air and blood round their birth. It is a top cause of death and life-long loss in the young.

Inside, scans show brain sores in such babes grow for days to weeks past birth. Late sores wear the marks of a set death path, with guard cells heaped round them. Bare death, not the neat cell death, rules those late sores in beast tests. Late cures in beasts, from cell grafts to calm drugs, cut the harm a lot. The team sees a wide cure span that past work has left untried.

Catalog record

CREATORBenjamin A Lear, Alice J McDouall, Olivia J Lear, Simerdeep K Dhillon, Christopher A Lear, Frances J Northington, Laura Bennet, Alistair J Gunn, Thomas Müller
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12731611

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