Off-Label NOACs vs. Antiplatelets in AF-Related Stroke with GFR < 15 mL/Min/1.73 m2: A Multicenter Outcome Study
Jong-Hee Sohn, Minwoo Lee, Chulho Kim, Joo Hye Sung, Kyung-Ho Yu, Yerim Kim, Hee Jung Mo, Jae Jun Lee, Sang-Hwa Lee, Cristina Gluhovschi · 2025
Read Off-Label NOACs vs. Antiplatelets in AF-Related Stroke with GFR < 15 mL/Min/1.73 m2: A Multicenter Outcome Study by Jong-Hee Sohn, Minwoo Lee, Chulho Kim, Joo Hye Sung, Kyung-Ho Yu, Yerim Kim, Hee Jung Mo, Jae Jun Lee, Sang-Hwa Lee, Cristina Gluhovschi (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12731138.txt.
Description
Jong-Hee Sohn and co-authors weighed two drug paths after stroke in patients with near failed kidneys in a 2025 study. The patients had a fluttering heart rhythm, the stroke cause, plus kidney function below a floor where standard blood thinners are not cleared for use. Doctors must pick between off label thinners and plain antiplatelet drugs.
A multi center stroke registry held three hundred eleven such patients. The thinner group saw about half the repeat stroke risk of the other group. Yet major bleeding ran more than three times higher, and deaths from all causes ran higher too, most from causes like sepsis. The authors urge case by case picks and close watch for this frail group.
Catalog record
| CREATOR | Jong-Hee Sohn, Minwoo Lee, Chulho Kim, Joo Hye Sung, Kyung-Ho Yu, Yerim Kim, Hee Jung Mo, Jae Jun Lee, Sang-Hwa Lee, Cristina Gluhovschi |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |