The Outcome and Impact of Academic Cancer Clinical Trials with Participation from Canadian Sites (2015–2024)
Rebecca Y Xu, Diana Kato, Victoria Percival, James Schoales, Stephen Sundquist, Raisa Chowdhury, Gregory R Pond, Janet E Dancey, Alan Hutson · 2025
Read The Outcome and Impact of Academic Cancer Clinical Trials with Participation from Canadian Sites (2015–2024) by Rebecca Y Xu, Diana Kato, Victoria Percival, James Schoales, Stephen Sundquist, Raisa Chowdhury, Gregory R Pond, Janet E Dancey, Alan Hutson (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12731042.txt.
Description
Rebecca Xu and co-authors audited a decade of academically run cancer trials with Canadian participation, asking what modest public money bought. A national network supported the trials on about 4.3 million Canadian dollars a year, roughly eleven cents per citizen, mostly from public sources. The team examined 350 trials that had finished recruiting between 2015 and 2024.
The returns look strong. Eighty-one percent of the trials were published, and forty-five percent posted results in public registries. Among the 116 largest phase three trials, thirty-six percent had already been written into clinical practice guidelines, with more likely to follow. The portfolio reached rare cancers and vulnerable patients that commercial sponsors often skip. The authors conclude that steady infrastructure, not blockbuster funding, is what lets academic trials finish, report, and change care. They offer the accounting as evidence for funders weighing similar networks.
Catalog record
| CREATOR | Rebecca Y Xu, Diana Kato, Victoria Percival, James Schoales, Stephen Sundquist, Raisa Chowdhury, Gregory R Pond, Janet E Dancey, Alan Hutson |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |