Longitudinal Changes in Brain Network Metrics and Their Correlations with Spinal Cord Diffusion Tensor Imaging Parameters Following Spinal Cord Injury and Regenerative Therapy
Ting Feng, Can Zhao, Wen-Nan Su, Yi-Meng Gao, Yuan-Yuan Wu, Wen Zhao, Jia-Sheng Rao, Zhao-Yang Yang, Xiao-Guang Li, Manisha Koneru, Marc Ekker, Hamza Adel Salim · 2025
Read Longitudinal Changes in Brain Network Metrics and Their Correlations with Spinal Cord Diffusion Tensor Imaging Parameters Following Spinal Cord Injury and Regenerative Therapy by Ting Feng, Can Zhao, Wen-Nan Su, Yi-Meng Gao, Yuan-Yuan Wu, Wen Zhao, Jia-Sheng Rao, Zhao-Yang Yang, Xiao-Guang Li, Manisha Koneru, Marc Ekker, Hamza Adel Salim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730989.txt.
Description
Ting Feng and co-authors track how the brain rewires after spinal cord injury, with and without a regenerative implant, in this 2025 study. A cut cord starves the brain of its usual traffic, and the brain's networks rearrange, sometimes badly. Eight monkeys received a half cut of the cord; half of them also received a growth-factor implant.
Scans of brain and cord ran over time alongside walking tests. Untreated animals settled into an over-segregated brain pattern with odd wiring and weak cord signals, the picture of maladaptive change. Treated animals kept healthier cord fibers and loosened that segregation. The implant also softened the abnormal links between brain measures and walking scores. Cord fiber quality itself predicted the brain's functional efficiency. The authors read recovery as a whole-system negotiation between cord and brain.
Catalog record
| CREATOR | Ting Feng, Can Zhao, Wen-Nan Su, Yi-Meng Gao, Yuan-Yuan Wu, Wen Zhao, Jia-Sheng Rao, Zhao-Yang Yang, Xiao-Guang Li, Manisha Koneru, Marc Ekker, Hamza Adel Salim |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |