Drosophila miR-33-5p Suppresses Cell Growth by Inhibiting ERK Signaling
Taeheon Lee, Nayeon Kim, Ye Jin Park, Seungeun Cha, Young Sik Lee, Do-Hwan Lim · 2025
Read Drosophila miR-33-5p Suppresses Cell Growth by Inhibiting ERK Signaling by Taeheon Lee, Nayeon Kim, Ye Jin Park, Seungeun Cha, Young Sik Lee, Do-Hwan Lim (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730946.txt.
Description
Taeheon Lee and co-authors find in 2025 that a small RNA in fruit flies curbs cell growth by blocking a growth signal path. Growth control steers survival, development, and repair, yet its full wiring stays partly unknown. The small RNA targets a switch gene in that path.
Extra copies of the RNA slow cell growth in lab cells and shrink fly wings. Cutting the RNA has the mirror effect, adding cells to the wing. Adding back the switch gene or a stuck-on signal rescues the wing fault. The chain from RNA to switch to signal now stands as a named growth axis.
Catalog record
| CREATOR | Taeheon Lee, Nayeon Kim, Ye Jin Park, Seungeun Cha, Young Sik Lee, Do-Hwan Lim |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |