Toxic Impacts of Trichlorfon on Tambaqui (Colossoma macropomum): Molecular Evidence of Oxidative, Metabolic and Apoptotic Stress
Hallana Cristina Menezes da Silva, Daniele Aparecida Matoso, André Gentil da Silva, Ana Lúcia Silva Gomes, Wallice Paxiúba Duncan, Roberto Ferreira Artoni · 2025
Read Toxic Impacts of Trichlorfon on Tambaqui (Colossoma macropomum): Molecular Evidence of Oxidative, Metabolic and Apoptotic Stress by Hallana Cristina Menezes da Silva, Daniele Aparecida Matoso, André Gentil da Silva, Ana Lúcia Silva Gomes, Wallice Paxiúba Duncan, Roberto Ferreira Artoni (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730929.txt.
Description
Hallana Silva and co-authors track gene switches flipped by a fish farm pesticide in a 2025 study. Trichlorfon controls parasites in aquaculture, but even doses too low to kill may poison the fish themselves. Tambaqui, a major Amazonian food fish, is a sensitive test case.
Juvenile fish swam in two sublethal doses for up to four days while liver gene activity was measured. Early on, stress and damage-control genes surged, along with energy and survival pathways, a compensation phase. By ninety-six hours, one energy gene collapsed while hypoxia and inflammation genes spiked late. The pattern shows initial coping giving way to metabolic failure. The authors propose the gene panel as an early-warning biomarker set for farm water monitoring.
Catalog record
| CREATOR | Hallana Cristina Menezes da Silva, Daniele Aparecida Matoso, André Gentil da Silva, Ana Lúcia Silva Gomes, Wallice Paxiúba Duncan, Roberto Ferreira Artoni |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |