Mixed-methods integration during data analysis in clinical trials of complex healthcare interventions: how is it done, and what can it do? Protocol for a systematic methodological review
Holly Victoria Rose Sugg, Naomi Shaw, Ellen M Vesterlund, Joanne Woodford · 2025
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Description
Holly Sugg and co-authors lay out a plan to review how mixed studies blend their number and word data mid-analysis. Their 2025 protocol deals with trials of complex health care, where word-based work often runs beside the trial. Blending the two strands at the analysis stage can reveal how a treatment works, why results vary, and what helps or blocks rollout. In practice such blending is rare, and its worth is underrated, the authors say.
The review will search seven databases and sort which blend tricks are used, whether they met each study's aims, and what insights each trick yields. Insight kinds span broad and narrow, and links between trick and yield will be checked, as will study quality.
Catalog record
| CREATOR | Holly Victoria Rose Sugg, Naomi Shaw, Ellen M Vesterlund, Joanne Woodford |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |