Understanding the pathogenesis of uveitis in Ebola virus disease survivors: an observational cohort and cross-sectional study protocol for clinical, molecular virologic and immunologic characterisation
Caleb D Hartley, Susanne Linderman, Tolulope Fashina, Laura Ward, Carolyn Drews-Botsch, Catherine Pratt, Sanjana Kuthyar, Alcides Filho Fernandes, Ye Huang, Charlene Choo, Nam Nguyen, Jessica Carag, Jill Morgan, Colleen S Kraft, Angela Hewlett, David Brett-Major, John S Schieffelin, Robert F Garry, · 2025
Read Understanding the pathogenesis of uveitis in Ebola virus disease survivors: an observational cohort and cross-sectional study protocol for clinical, molecular virologic and immunologic characterisation by Caleb D Hartley, Susanne Linderman, Tolulope Fashina, Laura Ward, Carolyn Drews-Botsch, Catherine Pratt, Sanjana Kuthyar, Alcides Filho Fernandes, Ye Huang, Charlene Choo, Nam Nguyen, Jessica Carag, Jill Morgan, Colleen S Kraft, Angela Hewlett, David Brett-Major, John S Schieffelin, Robert F Garry, (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730762.txt.
Description
Caleb D Hartley and a large team of co-authors set out a study of eye disease in Ebola survivors. Their 2025 protocol examines uveitis, a sight-threatening inflammation inside the eye. The West African outbreak of 2013 to 2016 left thousands of survivors. Virus lingering in the eye has been found long after blood clears.
The study pairs a cohort with cross-sectional checks of survivors. Clinical exams join virus hunting and immune profiling. The team asks how viral persistence and immune responses drive the eye disease. Sites and groups in the study span survivor care programs. Knowing the mechanism could guide treatment and follow-up for survivors. The protocol lays out the full plan before results arrive.
Catalog record
| CREATOR | Caleb D Hartley, Susanne Linderman, Tolulope Fashina, Laura Ward, Carolyn Drews-Botsch, Catherine Pratt, Sanjana Kuthyar, Alcides Filho Fernandes, Ye Huang, Charlene Choo, Nam Nguyen, Jessica Carag, Jill Morgan, Colleen S Kraft, Angela Hewlett, David Brett-Major, John S Schieffelin, Robert F Garry, |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |