Noninvasive Seizure Onset Zone Localization Using Janashia–Lagvilava Algorithm-Based Spectral Factorization in Granger Causality
Sofia Kasradze, Giorgi Lomidze, Lasha Ephremidze, Tamar Gagoshidze, Giorgi Japaridze, Maia Alkhidze, Tamar Jishkariani, Mukesh Dhamala · 2025
Read Noninvasive Seizure Onset Zone Localization Using Janashia–Lagvilava Algorithm-Based Spectral Factorization in Granger Causality by Sofia Kasradze, Giorgi Lomidze, Lasha Ephremidze, Tamar Gagoshidze, Giorgi Japaridze, Maia Alkhidze, Tamar Jishkariani, Mukesh Dhamala (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730380.txt.
Description
Sofia Kasradze and co-authors locate where seizures start in the brain using scalp recordings in a 2025 study. Finding the seizure onset zone guides surgery for patients whose epilepsy resists drugs. The usual method needs electrodes placed inside the skull. The team instead tracked information flow in scalp signals with a causality method built on a new factorization algorithm.
They studied six patients who were being assessed for surgery, across pairs of brain regions and short time windows. The method found the start zones and the paths seizures took from them. Its answers matched the good surgical outcomes seen in all six cases, each reaching the best outcome class. The authors see promise for safer planning and for wider studies of brain information flow.
Catalog record
| CREATOR | Sofia Kasradze, Giorgi Lomidze, Lasha Ephremidze, Tamar Gagoshidze, Giorgi Japaridze, Maia Alkhidze, Tamar Jishkariani, Mukesh Dhamala |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |