Temporal Dynamics of Inflammatory, Glial, and Metabolic Biomarkers Following Severe Diffuse Traumatic Brain Injury in a Rat Model
Ozan Başkurt, Brandon Lucke-Wold, Bruno Meloni · 2025
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Description
Ozan Başkurt, Brandon Lucke-Wold, and Bruno Meloni trace blood markers over time after severe brain injury in rats in a 2025 study. A hard blow sets off waves of swelling, support cell strain, and metabolic upset that worsen the first wound. The timing of those waves is the map this study draws.
Rats got a diffuse injury from a weight drop, or a sham one, and blood was drawn at set hours out to three days. Four markers were read: two swelling signals, one support cell protein, and insulin. One swelling signal dipped then peaked at a day. The curves sketch how the body answers in stages.
Catalog record
| CREATOR | Ozan Başkurt, Brandon Lucke-Wold, Bruno Meloni |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |