Chitosan-Based Nanoparticles and Biomaterials for Pulp Capping and Regeneration: A Systematic Review with Quantitative and Evidence-Mapping Synthesis
Saleh Ali Alqahtani, Mohammad Alamri, Ghadeer Alwadai, Naif N Abogazalah, Vinod Babu Mathew, Betsy Joseph, Bo Su · 2025
Read Chitosan-Based Nanoparticles and Biomaterials for Pulp Capping and Regeneration: A Systematic Review with Quantitative and Evidence-Mapping Synthesis by Saleh Ali Alqahtani, Mohammad Alamri, Ghadeer Alwadai, Naif N Abogazalah, Vinod Babu Mathew, Betsy Joseph, Bo Su (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730371.txt.
Description
Saving a tooth's living pulp beats root canal work when it is possible, and shellfish-derived chitosan may help. Saleh Alqahtani and co-authors review in 2025 sixteen controlled lab and animal studies of chitosan nanoparticles, gels, and scaffolds used to cap or regrow dental pulp. They graded bias and certainty with preclinical tools and mapped results by direction of effect.
Across studies, chitosan materials raised cell survival and mineral building and switched on tooth- and vessel-forming markers more than the standard cements. Animal work showed better blood vessel growth and repair tissue. Small samples and murky methods kept certainty low, so the team calls for stronger trials.
Catalog record
| CREATOR | Saleh Ali Alqahtani, Mohammad Alamri, Ghadeer Alwadai, Naif N Abogazalah, Vinod Babu Mathew, Betsy Joseph, Bo Su |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |