Sympathetic Regulation of Hematopoiesis and the Mobilization of Inflammatory Cells in ICR Mice with Traumatic Brain Injury: A Novel Approach to Targeting Neuroinflammation and Degenerative Processes
Natalia Ermakova, Victoria Skurikhina, Edgar Pan, Mariia Zhukova, Irina Zharkikh, Valentina Pan, Alexander Dygai, Roberto Paganelli · 2025
Read Sympathetic Regulation of Hematopoiesis and the Mobilization of Inflammatory Cells in ICR Mice with Traumatic Brain Injury: A Novel Approach to Targeting Neuroinflammation and Degenerative Processes by Natalia Ermakova, Victoria Skurikhina, Edgar Pan, Mariia Zhukova, Irina Zharkikh, Valentina Pan, Alexander Dygai, Roberto Paganelli (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730295.txt.
Description
Natalia Ermakova and co-authors study how nerve signals that drive blood cell release affect brain swelling after injury, in a mouse study from 2025. After a traumatic brain injury, swelling in the brain drives much of the later harm. Bone marrow makes immune cells that can add to that swelling.
Injured mice showed more white cells in blood, more cell making in marrow, and swelling and decay in brain areas. A drug that calms the nerve signal cut those changes. Fewer immune cells entered the brain, and fewer support cells turned to a harmful state. The work points to marrow control as a target after brain injury.
Catalog record
| CREATOR | Natalia Ermakova, Victoria Skurikhina, Edgar Pan, Mariia Zhukova, Irina Zharkikh, Valentina Pan, Alexander Dygai, Roberto Paganelli |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |