Isolation and Probiotic Functions of Bacillus subtilis and Its Inhibitory Effects on Colitis
Ningning Guan, Chang Li, Wei Liu, Qiong Wu, Jiajia Zhu, Ting Gao, Hui Song, Rui Guo, Fangyan Yuan, Yongxiang Tian, Keli Yang, Danna Zhou · 2025
Read Isolation and Probiotic Functions of Bacillus subtilis and Its Inhibitory Effects on Colitis by Ningning Guan, Chang Li, Wei Liu, Qiong Wu, Jiajia Zhu, Ting Gao, Hui Song, Rui Guo, Fangyan Yuan, Yongxiang Tian, Keli Yang, Danna Zhou (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730260.txt.
Description
Ningning Guan and eleven co-authors isolate a Bacillus subtilis strain from a goat farm and test its probiotic traits and anti colitis effects. The species is widely used as a feed additive in livestock and poultry. The new strain tolerates high heat, acid and alkali, and high bile salt levels, and it aggregates strongly within a day.
Genome sequencing maps genes for amino acid metabolism, vitamin synthesis, and other pathways. In mice with chemically induced colitis, the diseased group shows loss of gut barrier proteins and high inflammatory signals. Feeding the strain eases those changes in the treated animals. The work supports the isolate as a candidate probiotic for gut health in farm settings.
Catalog record
| CREATOR | Ningning Guan, Chang Li, Wei Liu, Qiong Wu, Jiajia Zhu, Ting Gao, Hui Song, Rui Guo, Fangyan Yuan, Yongxiang Tian, Keli Yang, Danna Zhou |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |