Click Detect: A Rapid and Sensitive Assay for Shiga Toxin 2 Detection
Benjamin M. Thomas, Emma L. Webb, Katherine L. Yan, Alexi M. Fernandez, Zhilei Chen · 2025
Read Click Detect: A Rapid and Sensitive Assay for Shiga Toxin 2 Detection by Benjamin M. Thomas, Emma L. Webb, Katherine L. Yan, Alexi M. Fernandez, Zhilei Chen (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730240.txt.
Description
Benjamin Thomas and co-authors published a study in 2025 on a fast test for a food-poison toxin. A gut germ that makes this toxin causes severe illness and can damage kidneys. Labs need cheap, quick ways to spot the toxin in food and water.
Their platform builds sensing probes in a single pot within two hours, at a cost of about four cents per test. A probe made this way pairs with a capture protein to form a sandwich test. Standard gene-copying readouts detected the toxin at very low levels. The test kept its edge in samples mixed with pool water or lettuce extract. The probe format can swap parts to hunt other targets. The authors see wide use in food checks and bedside testing.
Catalog record
| CREATOR | Benjamin M. Thomas, Emma L. Webb, Katherine L. Yan, Alexi M. Fernandez, Zhilei Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |