Morphofunctional Features of the Immune System Response to Sublethal Hypoxic Load in Hypoxia-Tolerant and Hypoxia-Susceptible Animals

Maria Kirillova, Dzhuliia Dzhalilova, Mariia Zubareva, Nikolai Fokichev, Olga Makarova · 2025

Read Morphofunctional Features of the Immune System Response to Sublethal Hypoxic Load in Hypoxia-Tolerant and Hypoxia-Susceptible Animals by Maria Kirillova, Dzhuliia Dzhalilova, Mariia Zubareva, Nikolai Fokichev, Olga Makarova (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12730225.txt.

Description

Maria Kirillova and four co-workers wrote a 2025 rat study on how the immune system answers a near-lethal low-oxygen test. Tolerance to low oxygen is often gauged in a low-pressure chamber at extreme simulated height. Rats differ in that tolerance. The team compared immune traits in tolerant and susceptible rats a month after the test.

Susceptible rats held more killer immune cells in blood and larger active zones in the spleen. They also showed higher levels of swelling signals in blood cells. Tolerant rats held more of a distinct antibody-making cell type. The split in response lasted well past the test itself.

Catalog record

CREATORMaria Kirillova, Dzhuliia Dzhalilova, Mariia Zubareva, Nikolai Fokichev, Olga Makarova
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12730225

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