Pyoderma gangrenosum associated with granulomatosis with polyangiitis: a case report

Marwa Ben Brahim, Sirine Abdellatif, Asma Ben Mabrouk, Olfa Jomaa, Azer Chebil, Mahdi Hasnaoui, Sondess Arfa, Olfa Berriche · 2025

Read Pyoderma gangrenosum associated with granulomatosis with polyangiitis: a case report by Marwa Ben Brahim, Sirine Abdellatif, Asma Ben Mabrouk, Olfa Jomaa, Azer Chebil, Mahdi Hasnaoui, Sondess Arfa, Olfa Berriche (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729807.txt.

Description

Marwa Ben Brahim and co-authors present a 2025 case report linking two rare diseases. Pyoderma gangrenosum is a painful ulcerating skin disorder in the neutrophilic family. Its causes are not fully understood. Its pairing with granulomatosis with polyangiitis, a vessel inflammation disease, is scarcely reported. The patient is a twenty-six-year-old Tunisian man. Two months of blocked, bloody nose trouble opened the case. Endoscopy found redness, crusting, and granulation inside the nose.

Biopsy showed chronic inflammation with tissue death, supporting the vessel disease in a localized form. Steroid pulses and cyclophosphamide began the treatment. The skin disease then entered the picture during his care. Clinicians get a documented pairing that widens the checklist when ulcers meet vessel inflammation. Rare pairings hide in single case reports until patterns emerge. Recording them with full workup detail is how the pattern library grows.

Catalog record

CREATORMarwa Ben Brahim, Sirine Abdellatif, Asma Ben Mabrouk, Olfa Jomaa, Azer Chebil, Mahdi Hasnaoui, Sondess Arfa, Olfa Berriche
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE9 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729807

Browse the full library · About the Tower of Babel