Methanol Extract from Ranunculus repens L. Down-Regulated Galectins 4 and 9, and Mitigated Chronic Pancreatitis in an Experimental Rat Model

Amir Khenchil, Hocine Rechreche, Arbia Abbes, Elisa Pettineo, Chiara Dianzani, Moufida Bensam, Widad Sobhi, Stefania Pizzimenti, Alessandra Napolitano · 2025

Read Methanol Extract from Ranunculus repens L. Down-Regulated Galectins 4 and 9, and Mitigated Chronic Pancreatitis in an Experimental Rat Model by Amir Khenchil, Hocine Rechreche, Arbia Abbes, Elisa Pettineo, Chiara Dianzani, Moufida Bensam, Widad Sobhi, Stefania Pizzimenti, Alessandra Napolitano (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729588.txt.

Description

Amir Khenchil and co-authors test a plant extract against long-term pancreas swelling in rats. The ill grinds on with scar growth and cell stress, and the plant, creeping buttercup, has a past in Algerian folk care for liver and sugar ills. Their 2025 study first maps what the extract holds, then feeds it into a rat model of the ill and into lab-grown pancreas cells.

Tissue checks use dyes that show harm and scar spread. Blood and tissue reads track stress marks and scar-linked genes. Two sugar-binding proteins tied to swelling drop under the extract, the team finds. Lab tests also weigh how well it fights cell stress and cell death. The work frames the plant as a lead worth more study, not yet a cure.

Catalog record

CREATORAmir Khenchil, Hocine Rechreche, Arbia Abbes, Elisa Pettineo, Chiara Dianzani, Moufida Bensam, Widad Sobhi, Stefania Pizzimenti, Alessandra Napolitano
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE59 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729588

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