Transcriptomic and Physiological Responses Reveal a Time-Associated Multi-Organ Injury Pattern in European Perch (Perca fluviatilis) Under Acute Alkaline Stress
Geng Chen, Yi Liu, Xiaodong Li, Pan Gao, Jianyong Hu, Pengfei Sun, Fangyuan Peng, Peng Chen, Jin Xu · 2025
Read Transcriptomic and Physiological Responses Reveal a Time-Associated Multi-Organ Injury Pattern in European Perch (Perca fluviatilis) Under Acute Alkaline Stress by Geng Chen, Yi Liu, Xiaodong Li, Pan Gao, Jianyong Hu, Pengfei Sun, Fangyuan Peng, Peng Chen, Jin Xu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729543.txt.
Description
Geng Chen and co-authors wrote a 2025 paper on how alkaline water harms a freshwater fish, the European perch. Around the world, some lakes and rivers are turning more alkaline, which stresses fish. The team exposed perch to strong alkaline water and tracked the damage organ by organ over ninety-six hours.
The gills failed first, with their fine blades fusing and dying, which hurt the fish's salt balance. The liver followed, with rising oxidative damage and widespread cell death. Gene readings showed thousands of changed genes in the liver and hundreds in the kidney. The time-ordered pattern, gills then liver then kidney, helps explain how this stress kills and may guide fishery warnings.
Catalog record
| CREATOR | Geng Chen, Yi Liu, Xiaodong Li, Pan Gao, Jianyong Hu, Pengfei Sun, Fangyuan Peng, Peng Chen, Jin Xu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |