Comparative Analysis of Two Measurement Modalities for Ex Vivo Analysis of Corneal Stiffness in Porcine Corneas
Sophia A Reifeltshammer, Hannah Seferovic, Malavika H Nambiar, Philippe Büchler, Theo G Seiler, Jascha Wendelstein, Matthias Bolz, Peter Hinterdorfer, Yoo Jin Oh, Isaak Fischinger, Dimitrios Karamichos · 2025
Read Comparative Analysis of Two Measurement Modalities for Ex Vivo Analysis of Corneal Stiffness in Porcine Corneas by Sophia A Reifeltshammer, Hannah Seferovic, Malavika H Nambiar, Philippe Büchler, Theo G Seiler, Jascha Wendelstein, Matthias Bolz, Peter Hinterdorfer, Yoo Jin Oh, Isaak Fischinger, Dimitrios Karamichos (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729501.txt.
Description
A research team compares two ways to measure cornea stiffness in this 2025 study. The cornea can be stiffened by crosslinking treatment, and labs need to know which test reads the change best, at the whole tissue level or at tiny spots.
Sixty-two pig corneas were split into untreated, standard crosslinking, and accelerated crosslinking groups. Pull tests showed clear stiffening, with the standard group up ninety-six percent at a set strain. A nanoindentation microscope, which probes tiny areas, found smaller, non-significant rises. The authors conclude the pull test gives the robust global read, while the probe maps local detail, so the choice depends on the question.
Catalog record
| CREATOR | Sophia A Reifeltshammer, Hannah Seferovic, Malavika H Nambiar, Philippe Büchler, Theo G Seiler, Jascha Wendelstein, Matthias Bolz, Peter Hinterdorfer, Yoo Jin Oh, Isaak Fischinger, Dimitrios Karamichos |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |