Wound-Healing Potential of Engineered Lysin GRC-ML07 in Pseudomonas aeruginosa Infected Wounds in Immunocompromised Mice
Mariam Abdulkadieva, Darya Slonova, Veronika Litvinenko, Nataliia Antonova, Elena Mazunina, Konstantin Sobyanin, Tatiana Guseva, Olga Parshina, Pavel Domnin, Vladislav Poloskov, Vladimir Guschin, Daria Vasina, Elena Sysolyatina, Alexander Gintsburg · 2025
Read Wound-Healing Potential of Engineered Lysin GRC-ML07 in Pseudomonas aeruginosa Infected Wounds in Immunocompromised Mice by Mariam Abdulkadieva, Darya Slonova, Veronika Litvinenko, Nataliia Antonova, Elena Mazunina, Konstantin Sobyanin, Tatiana Guseva, Olga Parshina, Pavel Domnin, Vladislav Poloskov, Vladimir Guschin, Daria Vasina, Elena Sysolyatina, Alexander Gintsburg (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729281.txt.
Description
Mariam Abdulkadieva and a large team test an engineered lysin on infected wounds in a 2025 paper. Mice with weakened immune systems carried full-thickness wounds. The wounds were infected with drug-resistant Pseudomonas bacteria.
The lysin, a bacteria-killing enzyme, sat inside an alginate gel. The gel was applied twice daily for four days. Healing speed and bacterial load were the main checks. Resistant wound infections are a growing threat in hospitals. Enzyme therapy offers an antibiotic-free line of attack. Readers see animal evidence for a gel that fights infection while tissue closes.
Catalog record
| CREATOR | Mariam Abdulkadieva, Darya Slonova, Veronika Litvinenko, Nataliia Antonova, Elena Mazunina, Konstantin Sobyanin, Tatiana Guseva, Olga Parshina, Pavel Domnin, Vladislav Poloskov, Vladimir Guschin, Daria Vasina, Elena Sysolyatina, Alexander Gintsburg |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |