Association between vitamin D and metabolic-associated steatotic liver disease in type 2 diabetes mellitus patients: a systematic review and meta-analysis

Bruno Basil, Winifred Adiri, Ejike Lawrence Ugwu, Ngozi Ijeoma Okoro · 2025

Read Association between vitamin D and metabolic-associated steatotic liver disease in type 2 diabetes mellitus patients: a systematic review and meta-analysis by Bruno Basil, Winifred Adiri, Ejike Lawrence Ugwu, Ngozi Ijeoma Okoro (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729236.txt.

Description

Bruno Basil, Winifred Adiri, Ejike Lawrence Ugwu, and Ngozi Ijeoma Okoro pool the evidence on whether low vitamin D travels with fatty liver disease in people who have type 2 diabetes. The vitamin's deficiency is a plausible, fixable contributor to liver fat, but the diabetes-specific literature disagrees. Their search of records from two thousand to twenty twenty-five found ten qualifying studies covering over four thousand participants.

Most studies came from Asia and the Middle East. Pooling showed patients with fatty liver disease had significantly lower circulating vitamin D than those without, with roughly a half-standard-deviation gap. Liver status came from imaging, elastography, or biomarker scores. The authors flag the geographic narrowness as the evidence base's main weakness.

Catalog record

CREATORBruno Basil, Winifred Adiri, Ejike Lawrence Ugwu, Ngozi Ijeoma Okoro
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729236

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