Respiratory potentially pathogenic bacteria are associated with increased disease severity in neonates with respiratory syncytial virus infection

Xiaofeng Yang, Lei Ding, Xin Ding · 2025

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Description

Xiaofeng Yang, Lei Ding, and Xin Ding study whether airway bacteria worsen respiratory syncytial virus disease in neonates. The virus is a leading cause of lower airway infection in infants under two years. A retrospective cohort at one childrens hospital covers cases from July 2017 to June 2024.

Among 4,091 neonates with lower airway infection, 542 test positive for the virus, and 123 of those are severe. Presence of potentially pathogenic bacteria in virus positive babies links to more high fever, feeding difficulty, heart complications, and oxygen need. Oxygen therapy lasts longer and intensive care admission is more common when bacteria are present. Three species dominate detections, and one species shows a strong severity link in the data.

Catalog record

CREATORXiaofeng Yang, Lei Ding, Xin Ding
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE24 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729202

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