Immunogenicity of a bivalent recombinant adenovirus expressing VP1 proteins of bovine norovirus and bovine nebovirus in mice and calves
Taoyun Chen, Jun Chu, Xin Song, Qisheng Yu, Gunan Deng, Jiangyong Zeng, Changqing Yu, Bin Zhang · 2025
Read Immunogenicity of a bivalent recombinant adenovirus expressing VP1 proteins of bovine norovirus and bovine nebovirus in mice and calves by Taoyun Chen, Jun Chu, Xin Song, Qisheng Yu, Gunan Deng, Jiangyong Zeng, Changqing Yu, Bin Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729173.txt.
Description
Taoyun Chen and seven co-authors present a 2025 study of a two in one vaccine for calves against two gut viruses. Both viruses are rising causes of severe diarrhea in young cattle around the world. A single shot that covers both could ease farm losses.
The team built the vaccine inside a weakened carrier virus. The carrier was fitted with a surface protein gene from each target virus. They gave the vaccine to mice and calves by muscle shot and by mouth. Blood tests showed strong antibody rises within two weeks of the shot. Levels peaked at high values in both routes, the authors report.
Catalog record
| CREATOR | Taoyun Chen, Jun Chu, Xin Song, Qisheng Yu, Gunan Deng, Jiangyong Zeng, Changqing Yu, Bin Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |