Differential associations of cumulative average metabolic score for insulin resistance with heart disease and stroke: a prospective cohort study of middle-aged and older Chinese adults

Chun Yang, Zeng Guo, Mengqing Ma, Shiyu Jin, Shuyi Zhang, Ling Xia, Longfeng Xia, Xianhe Lin · 2025

Read Differential associations of cumulative average metabolic score for insulin resistance with heart disease and stroke: a prospective cohort study of middle-aged and older Chinese adults by Chun Yang, Zeng Guo, Mengqing Ma, Shiyu Jin, Shuyi Zhang, Ling Xia, Longfeng Xia, Xianhe Lin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729148.txt.

Description

Chun Yang and co-authors study a long term insulin resistance score and heart disease in Chinese adults in a 2025 paper. Insulin resistance is a known risk factor for cardiovascular disease, and a metabolic score can stand in for it. Whether years of high scores predict new disease was unexplored in China. The team followed 5264 middle aged and older adults from a national aging study.

Over four years, about ten percent developed cardiovascular disease. Higher average scores across two measures years apart raised total disease risk in a dose pattern. The top score group faced higher heart disease risk but no clear stroke risk. Risk was sharper in men, smokers, drinkers, and people with normal blood pressure. Readers see value in tracking the score over time.

Catalog record

CREATORChun Yang, Zeng Guo, Mengqing Ma, Shiyu Jin, Shuyi Zhang, Ling Xia, Longfeng Xia, Xianhe Lin
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE44 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729148

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