Prediction and analysis of anti-aging peptides using data augmentation and machine learning algorithms

Zhiyuan Zhang, Yuanyuan Chen, Shihao Wang, Guozhong Chen, Mingyang Wang, Yuanyuan Pan, Erguang Li · 2025

Read Prediction and analysis of anti-aging peptides using data augmentation and machine learning algorithms by Zhiyuan Zhang, Yuanyuan Chen, Shihao Wang, Guozhong Chen, Mingyang Wang, Yuanyuan Pan, Erguang Li (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729081.txt.

Description

Zhiyuan Zhang and co-authors present a 2025 study on finding peptides that may slow aging. Peptides are short chains the body can use as drugs, and anti-aging ones draw interest for their low risk of immune response and ease of making. Few computer tools exist to spot them, which slows the search.

The team built a test set from known cases and a public aging database, then trained three models to sort new peptides. One model learns rich features from each chain; the other two add fake or altered data to make training stronger. All three models scored very high on test sets. The authors offer them as tools to speed the hunt for fresh candidates.

Catalog record

CREATORZhiyuan Zhang, Yuanyuan Chen, Shihao Wang, Guozhong Chen, Mingyang Wang, Yuanyuan Pan, Erguang Li
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12729081

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