Comments on “The effects of norepinephrine in shockable cardiac arrest, a scoping review”
Samantha Camp, Caitlin Williams, Ali Pourmand, Quincy K. Tran · 2025
Read Comments on “The effects of norepinephrine in shockable cardiac arrest, a scoping review” by Samantha Camp, Caitlin Williams, Ali Pourmand, Quincy K. Tran (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12729065.txt.
Description
Samantha Camp and co-authors write a letter in two thousand twenty-five commenting on a review of norepinephrine in cardiac arrest. The drug is sometimes used when the heart's rhythm can be shocked. The original review leaned heavily on old animal studies to suggest benefit.
The letter argues that this base is too weak for clinical claims. Human data are scarce and vary widely in dose and delivery route. A recent pooled analysis found no clear survival or brain outcome advantage over epinephrine, the standard drug. Claims about brain outcomes rested on animal blood flow measures, not human evidence. The authors urge cautious reading of the review's conclusions.
Catalog record
| CREATOR | Samantha Camp, Caitlin Williams, Ali Pourmand, Quincy K. Tran |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 6 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |