Study on the antibacterial effect of the new anti-biofilm inhibitor ICAC on Escherichia coli
Yubin Bai, Zixuan Shang, Rongbin Hu, Xun Gao, Zhijin Zhang, Bing Li, Zhen Zhu, Jiyu Zhang · 2025
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Description
Yubin Bai and co-authors test a plant phenolic compound against Escherichia coli biofilms, the slime cities that shield bacteria from drugs, in work from twenty twenty-five. Antibiotic resistance keeps rising, and natural compounds are a hunted source of fresh weapons. The compound is isochlorogenic acid C from plants.
Stains, microscopes, and gene readouts traced its attack. It blocked new biofilm growth and shrank established films. Output of slime sugars and proteins fell, and swimming motility dropped. Gene checks showed it dialing down a key biofilm signal's production and dialing up its breakdown. The authors nominate it as an anti signal agent and a candidate for treating Escherichia coli infections.
Catalog record
| CREATOR | Yubin Bai, Zixuan Shang, Rongbin Hu, Xun Gao, Zhijin Zhang, Bing Li, Zhen Zhu, Jiyu Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |