Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers
Ion Antohe, Amalia Titieanu, Vlad Andrei Cianga, Cosmin Minciună, Cătălin Dănăilă, Alina Daniela Tănase, Iuliu Ivanov, Loredana Dragoş, Mihaela Zlei, Mihaela Mențel, Ciprian Tomuleasa, Anamaria Bancos, Manuela Ciocoiu, Angela Dăscălescu · 2025
Read Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers by Ion Antohe, Amalia Titieanu, Vlad Andrei Cianga, Cosmin Minciună, Cătălin Dănăilă, Alina Daniela Tănase, Iuliu Ivanov, Loredana Dragoş, Mihaela Zlei, Mihaela Mențel, Ciprian Tomuleasa, Anamaria Bancos, Manuela Ciocoiu, Angela Dăscălescu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12728000.txt.
Description
Ion Antohe and co-authors report real-world results for two immune drugs in hard-to-treat leukemia in a 2025 study. Adults whose B-cell leukemia returns or resists care face poor odds. The two drugs revived hope, but their best order and safety handling outside trials remain open questions.
Records cover thirty-three patients treated at two Romanian cancer centers between 2019 and 2023. One drug achieved full remission in about half its patients. The other reached remission in nine of ten, and most responders cleared measurable disease. The second drug worked best in early relapse and heavy disease. The first held value in other settings. Findings from a resource-limited system add practical guidance on sequencing and transplant links.
Catalog record
| CREATOR | Ion Antohe, Amalia Titieanu, Vlad Andrei Cianga, Cosmin Minciună, Cătălin Dănăilă, Alina Daniela Tănase, Iuliu Ivanov, Loredana Dragoş, Mihaela Zlei, Mihaela Mențel, Ciprian Tomuleasa, Anamaria Bancos, Manuela Ciocoiu, Angela Dăscălescu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |