Efficacy and safety assessment of gelatin hemostatic matrix in a burr hole neurosurgical beagle model
Jun Ma, Shaolei Gan, Ruming Shu, Liangbin Zhou, Shangsi Chen · 2025
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Description
Jun Ma and co-authors test two gelatin hemostatic matrices head-to-head in beagle dogs undergoing brain surgery, in a 2025 study. Bleeding control in neurosurgery is vital, and absorbable sponges that staunch blood are standard tools. Burr holes were treated with either SURGIFLO, the market leader, or Borayerflo, a Chinese rival.
Both products stopped bleeding fully within five minutes in every case, with no statistical gap between them. Blood tests of clotting times and fibrinogen showed neither matrix interfered with normal coagulation. No adverse reactions appeared after surgery. The authors conclude the challenger matches the incumbent on preclinical safety and power, making it a credible alternative product for surgical bleeding control.
Catalog record
| CREATOR | Jun Ma, Shaolei Gan, Ruming Shu, Liangbin Zhou, Shangsi Chen |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |