Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov
Yinghong Zhou, Zhaoxin Liu, Ji Xu, Ying Zhang, Haiqi Shen, Siyu Jiang, Yunyun Shi, Yinghua Lv, Jihan Huang · 2025
Read Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov by Yinghong Zhou, Zhaoxin Liu, Ji Xu, Ying Zhang, Haiqi Shen, Siyu Jiang, Yunyun Shi, Yinghua Lv, Jihan Huang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12727638.txt.
Description
Drug trials in children follow their own rules, since doses, forms, and delivery must suit small and growing bodies. Yinghong Zhou and co-authors chart a decade of such trials in a 2025 study of a global trial registry. They kept trials that tested drugs as a cure and enrolled only children, first posted from 2015 to 2024.
Close to three thousand trials made the cut, and yearly counts drifted down over the decade. Most enrolled one hundred children or fewer. Mind and behavior disorders formed the largest field across all trial stages. Liquid forms led, and swallowing was the top route, though pills and swallowing grew more common as the age band rose. The authors say the field needs a lift, with forms matched better to each age.
Catalog record
| CREATOR | Yinghong Zhou, Zhaoxin Liu, Ji Xu, Ying Zhang, Haiqi Shen, Siyu Jiang, Yunyun Shi, Yinghua Lv, Jihan Huang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |