Cognitive subgroups in bipolar disorder: associations with brain-derived neurotrophic factor and C-reactive protein
Ahmet Mete Demir, Yasemin Görgülü, Kübra Söğüt, Orkide Palabıyık, Elif Ayduk Gövdeli · 2025
Read Cognitive subgroups in bipolar disorder: associations with brain-derived neurotrophic factor and C-reactive protein by Ahmet Mete Demir, Yasemin Görgülü, Kübra Söğüt, Orkide Palabıyık, Elif Ayduk Gövdeli (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12724086.txt.
Description
Ahmet Mete Demir and co-authors sort bipolar patients by thinking profile in a 2025 study. One hundred forty-nine patients took a full battery of cognitive tests. Forty-eight healthy controls took the same tests. Blood was drawn from everyone for two markers. One marker is a growth factor tied to brain plasticity. The other is a protein that signals inflammation.
Clustering found three groups of patients. One group thought intactly. One was impaired in selected areas. One was impaired across the board. The middle group carried the highest growth factor levels. The worst group carried the highest inflammation levels. A cutoff on the inflammation marker flagged global impairment with fair accuracy. Readers get blood-linked subtypes for bipolar cognition.
Catalog record
| CREATOR | Ahmet Mete Demir, Yasemin Görgülü, Kübra Söğüt, Orkide Palabıyık, Elif Ayduk Gövdeli |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |