PREVENIR-IVF: study protocol for a prospective multicentre randomized open comparative trial, which explores the efficacy of a multidisciplinary platform reducing and preventing reprotoxic environmental exposures in subfertile couples on live birth rate after assisted reproduction treatment
Claire Sunyach, Blandine Courbiere, Nicolas Simon, Fleur Delva, Ronan Garlantezec, Florence Bretelle, Roger Leandri, Jean-François Gehanno, Yolande Esquirol, Sandrine Loubiere, Noémie Resseguier, Irène Sari-Minodier, Jeanne Perrin · 2025
Read PREVENIR-IVF: study protocol for a prospective multicentre randomized open comparative trial, which explores the efficacy of a multidisciplinary platform reducing and preventing reprotoxic environmental exposures in subfertile couples on live birth rate after assisted reproduction treatment by Claire Sunyach, Blandine Courbiere, Nicolas Simon, Fleur Delva, Ronan Garlantezec, Florence Bretelle, Roger Leandri, Jean-François Gehanno, Yolande Esquirol, Sandrine Loubiere, Noémie Resseguier, Irène Sari-Minodier, Jeanne Perrin (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12723840.txt.
Description
Claire Sunyach and a large team lay out a trial testing whether cutting environmental exposures improves IVF success, in this 2025 study protocol. Chemical, physical and lifestyle exposures at work and home can impair fertility, and many are fixable. The French PREVENIR platform screens couples for such risks and builds personal prevention plans.
Over two thousand subfertile couples starting IVF will be randomized: one arm uses the platform before the first treatment cycle, the other follows standard care. The main outcome is live birth rate after assisted reproduction. The design tests whether systematic exposure reduction, delivered by a multidisciplinary team, turns into more babies for couples in fertility treatment.
Catalog record
| CREATOR | Claire Sunyach, Blandine Courbiere, Nicolas Simon, Fleur Delva, Ronan Garlantezec, Florence Bretelle, Roger Leandri, Jean-François Gehanno, Yolande Esquirol, Sandrine Loubiere, Noémie Resseguier, Irène Sari-Minodier, Jeanne Perrin |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 67 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |