Mitigating nickel-induced toxicity: the protective role of native probiotic strains on oxidative stress and inflammatory pathways in mice lung tissues

Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Niloofar Rezaie, Shokufeh Beglari, Shadi Aghamohammad, Mahdi Rohani · 2025

Read Mitigating nickel-induced toxicity: the protective role of native probiotic strains on oxidative stress and inflammatory pathways in mice lung tissues by Fatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Niloofar Rezaie, Shokufeh Beglari, Shadi Aghamohammad, Mahdi Rohani (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12723828.txt.

Description

Fatemeh Haririzadeh Jouriani and co-authors test whether friendly gut germs can protect lungs from nickel harm, in a study from 2025. Nickel in air and at work can stress lung tissue and spark swelling. The team asked if native probiotic strains, given after exposure, could calm that harm in mice.

Male mice were exposed to nickel for sixty days and then given the probiotics. The team read gene activity in lung tissue to track stress and swelling signals. Nickel lowered the activity of genes that guard cells from stress. The probiotic treatment raised that activity back up. The results suggest these strains may help guard lungs, though the work was done only in mice.

Catalog record

CREATORFatemeh Haririzadeh Jouriani, Elham Haj Agha Gholizadeh Khiavi, Niloofar Rezaie, Shokufeh Beglari, Shadi Aghamohammad, Mahdi Rohani
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12723828

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