Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress
Qiaoyi Chen, Yukun Huang, Zhiya Yu, Wenjie He, Xueqin Hu, Jinhui Wu, Tianguang Cai, Yuhua Cui, Along Gao, Hu Shu · 2025
Read Transcriptome analysis reveals physiological responses in liver tissues of Epinephelus cyanopodus under acute hypoxic stress by Qiaoyi Chen, Yukun Huang, Zhiya Yu, Wenjie He, Xueqin Hu, Jinhui Wu, Tianguang Cai, Yuhua Cui, Along Gao, Hu Shu (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12723406.txt.
Description
Ten researchers studied how a farmed grouper responds when water oxygen drops sharply, in a 2025 paper. Oxygen in water shapes whether fish farming can stay productive and sustainable. The team held healthy blue-spotted groupers in normal water or low-oxygen water for up to nine hours and sampled their livers.
Gene activity readings found over six thousand genes whose activity shifted under low oxygen. The biggest body changes came at three to six hours of stress. Shifted genes clustered in paths for energy use, immune defense, and cell death control. Several liver enzymes also spiked at the three and six hour marks, backing the gene data. The authors say the three to six hour window is when the fish's response peaks. Their map of the response could guide breeding of hardier fish.
Catalog record
| CREATOR | Qiaoyi Chen, Yukun Huang, Zhiya Yu, Wenjie He, Xueqin Hu, Jinhui Wu, Tianguang Cai, Yuhua Cui, Along Gao, Hu Shu |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |