Safety and efficacy of oral anticoagulation in patients with intracranial hemorrhage and atrial fibrillation: a systematic review and meta-analysis of randomized controlled clinical trials
Nikolaos M. Papageorgiou, Lina Palaiodimou, Aikaterini Theodorou, Eleni Bakola, Maria Chondrogianni, Georgia Papagiannopoulou, Apostolos Safouris, Eleni Anagnou, Panagiota-Eleni Tsalouchidou, Effrosyni Koutsouraki, Theodore Karapanayiotides, Efstathios Boviatsis, Christos Krogias, Sotirios Giannopou · 2025
Read Safety and efficacy of oral anticoagulation in patients with intracranial hemorrhage and atrial fibrillation: a systematic review and meta-analysis of randomized controlled clinical trials by Nikolaos M. Papageorgiou, Lina Palaiodimou, Aikaterini Theodorou, Eleni Bakola, Maria Chondrogianni, Georgia Papagiannopoulou, Apostolos Safouris, Eleni Anagnou, Panagiota-Eleni Tsalouchidou, Effrosyni Koutsouraki, Theodore Karapanayiotides, Efstathios Boviatsis, Christos Krogias, Sotirios Giannopou (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12722659.txt.
Description
Nikolaos Papageorgiou and co-authors review blood thinner use after brain bleeding in patients with an irregular heartbeat in a 2025 combined analysis of trials. Atrial fibrillation raises clot and stroke risk, so many patients need anticoagulant drugs. After a brain hemorrhage, those same drugs raise the risk of bleeding again, creating a hard trade-off.
The team gathered randomized controlled trials on starting oral anticoagulants in this patient group. They weighed safety and benefit together across the trials using standard combined methods. The combined evidence helps doctors judge when restarting a blood thinner protects a patient more than it endangers them over time.
Catalog record
| CREATOR | Nikolaos M. Papageorgiou, Lina Palaiodimou, Aikaterini Theodorou, Eleni Bakola, Maria Chondrogianni, Georgia Papagiannopoulou, Apostolos Safouris, Eleni Anagnou, Panagiota-Eleni Tsalouchidou, Effrosyni Koutsouraki, Theodore Karapanayiotides, Efstathios Boviatsis, Christos Krogias, Sotirios Giannopou |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |