Immunomodulatory effect of ultrasound-guided cryoablation in early breast cancer: pilot study on blood and surgical samples
Federica Pediconi, Francesca Galati, Marianna Nuti, Veronica Rizzo, Andrea Botticelli, Lucrezia Tuosto, Angelica Pace, Aurelia Rughetti, Giulia d’Amati, Bruna Cerbelli, Chiara Napoletano · 2025
Read Immunomodulatory effect of ultrasound-guided cryoablation in early breast cancer: pilot study on blood and surgical samples by Federica Pediconi, Francesca Galati, Marianna Nuti, Veronica Rizzo, Andrea Botticelli, Lucrezia Tuosto, Angelica Pace, Aurelia Rughetti, Giulia d’Amati, Bruna Cerbelli, Chiara Napoletano (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12722633.txt.
Description
Federica Pediconi and co-authors run a pilot study on how freezing tumors affects the immune system in early breast cancer, in work from 2025. The method, guided by ultrasound, kills tumor tissue through freeze and thaw cycles. Dead tumor material may stir an immune response that helps fight the disease.
Ten patients with small, node negative tumors had the freezing treatment and then surgery to remove the tumor. Blood and tissue samples were taken at four time points around care. Lab tests tracked immune cell types, including regulatory cells and activated T cells. Blood signals tied to cell damage and immune alerts were also measured.
Catalog record
| CREATOR | Federica Pediconi, Francesca Galati, Marianna Nuti, Veronica Rizzo, Andrea Botticelli, Lucrezia Tuosto, Angelica Pace, Aurelia Rughetti, Giulia d’Amati, Bruna Cerbelli, Chiara Napoletano |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |