Surgical outcomes and prognostic factors in 228 patients with brain metastases: a focus on en bloc resection and multimodal therapy
Peng Sun, Chunyu Gu, Haoran Wang, Yanzhen Zhang, Jianping Cao, Junpeng Ji, Mingshan Zhang · 2025
Read Surgical outcomes and prognostic factors in 228 patients with brain metastases: a focus on en bloc resection and multimodal therapy by Peng Sun, Chunyu Gu, Haoran Wang, Yanzhen Zhang, Jianping Cao, Junpeng Ji, Mingshan Zhang (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12722606.txt.
Description
Cancer that has spread to the brain can sometimes be removed by surgery, and what happens around that surgery shapes survival. Peng Sun and co-authors reviewed 228 patients who had brain metastases removed at one hospital between 2012 and 2020. They tracked survival and tested which factors, including surgical technique and the order of other treatments, predicted how patients fared.
Median survival was fourteen months. A patient's functional score before surgery was the strongest predictor of outcome. Radiation after surgery stretched median survival to eighteen months, and a small group treated before and after surgery reached forty-one months. In lung cancer cases, targeted therapy also linked to much longer survival. The authors favor aggressive, combined treatment.
Catalog record
| CREATOR | Peng Sun, Chunyu Gu, Haoran Wang, Yanzhen Zhang, Jianping Cao, Junpeng Ji, Mingshan Zhang |
|---|---|
| YEAR | 2025 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |