Interplay Between Enteroendocrine Hormone (Leptin) and Adipokines (Ghrelin and Adiponectin) with Gastric Expression of FTO and MC4R Genes

Mohamed Hany, Mona K. ElDeeb, Ehab Elmongui, Anwar Ashraf Abouelnasr, Noha A. El-Banna, Sahar M. Omer, Sara A. Shaker, Rasha A. ElTahan · 2025

Read Interplay Between Enteroendocrine Hormone (Leptin) and Adipokines (Ghrelin and Adiponectin) with Gastric Expression of FTO and MC4R Genes by Mohamed Hany, Mona K. ElDeeb, Ehab Elmongui, Anwar Ashraf Abouelnasr, Noha A. El-Banna, Sahar M. Omer, Sara A. Shaker, Rasha A. ElTahan (2025) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-12722424.txt.

Description

Mohamed Hany and co-authors present a 2025 case-control study of obesity and the stomach. The team asked how two genes tied to body weight, named FTO and MC4R, act in stomach tissue, and how that action links to three signals in the blood.

The study drew on fifty patients who had weight-loss stomach surgery and fifty people who had a scope exam for other reasons. Tests on tissue and blood showed FTO turned up far more in the obesity group, while MC4R was turned down far more. One blood signal, tied to fat tissue, ran high in the same group and tracked with weight and a good form of blood fat. The authors read the pattern as a sign that stomach gene action may shape weight-linked health risks.

Catalog record

CREATORMohamed Hany, Mona K. ElDeeb, Ehab Elmongui, Anwar Ashraf Abouelnasr, Noha A. El-Banna, Sahar M. Omer, Sara A. Shaker, Rasha A. ElTahan
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC12722424

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